تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Evaluation of InnoTyper® 21 in a sample of Rio de Janeiro population as an alternative forensic panel
Evaluation of InnoTyper® 21 in a sample of Rio de Janeiro population as an alternative forensic panel
 
لغة الوثيقة : الانجليزية 
المستخلص : The use of bi-allelic markers such as retrotransposable element insertion polymorphisms or Innuls (for insertion/null) can overcome some limitations of short tandem repeat (STR) loci in typing forensic biological evidence. This study investigated the efficiency of the InnoTyper® 21 Innul markers in an urban admixed population sample in Rio de Janeiro (n = 40) and one highly compromised sample collected as evidence by the Rio de Janeiro police. No significant departures from Hardy-Weinberg equilibrium were detected after the Bonferroni correction (α′ ≈ 0.05/20, p < 0.0025), and no significant linkage disequilibrium was observed between markers. Assuming loci independence, the cumulative random match probability (RMP) was 2.3 × 10−8. A lower mean Fis value was obtained for this sample population compared with those of three North American populations (African-American, Southwest Hispanic, US Caucasian). Principal component analysis with the three North American populations and one from 21 East Asian population showed that African Americans segregated as an independent group while US Caucasian, Southwest Hispanic, East Asian, and Rio de Janeiro populations are in a single large heterogeneous group. Also, a full Innuls profile was produced from an evidence sample, despite the DNA being highly degraded. In conclusion, this system is a useful complement to standard STR kits. 
ردمد : 1437-1596 
اسم الدورية : International Journal of Legal Medicine 
المجلد : 132 
العدد : 1 
سنة النشر : 1439 هـ
2018 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Thursday, June 20, 2019 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
Rodrigo S. Moura-NetoMoura-Neto, Rodrigo S.باحث رئيسيدكتوراهrodrigomouraneto@ufrj.br
I. C. T. MelloT. Mello, I. C.باحثدكتوراه 
Rosane SilvaSilva, Rosane باحثدكتوراه 
Carolina G. BottinoBottino, Carolina G.باحثدكتوراه 
A. WoernerWoerner, A. باحثدكتوراه 
Jonathan L KingKing, Jonathan Lباحثدكتوراه 
Frank WendtWendt, Frank باحثدكتوراه 
Bruce BudowleBudowle, Bruce باحثدكتوراه 

الملفات

اسم الملفالنوعالوصف
 44509.pdf pdf 

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